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In the fight against COVID-19, Dr. Jerome Baudry, Ms. Pei-Ling Chan Chair and Professor in the Department of Biological Sciences at The University of Alabama in Huntsville (UAH), is leveraging computational tools to significantly reduce time to study critical stages of drug design on our path to a cure. And he’s inviting us all along for the ride.
VIDEO: Dr. Jerome Baudry begins chronicling his mission to COVID-19 drug discovery
Forming a formidable attack against COVID-19
Dr. Baudry, a distinguished researcher in molecular biophysics, is taking a molecular docking approach to predict the binding – or “lock and key” interaction – between the viral protein in the coronavirus and molecules that can counterattack its functions.
The molecules that he and his team are using can be found in chemical compounds and other natural elements in plants, fungi, and sometimes animals, to understand how they can be applied to drug development. They’re researching the efficacy of these natural products in attacking the COVID-19 protein to figure out which ones can help to treat or mitigate the effects of the virus. These outcomes are then further tested in pre-clinical and clinical studies.
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