2-Bromophenylboronic acid (CAS 244205-40-1) is an aromatic boronic acid used as a building block in organic synthesis, particularly when a route needs both a boronic acid group and an aryl bromide on the same benzene ring. The boronic acid group can participate in palladium-catalyzed Suzuki–Miyaura coupling, while the bromide can provide a separate site for further functionalization. Its molecular formula is C6H6BBrO2, and its molecular weight is approximately 200.83 g/mol. For purchasing, confirm the required grade, assay method, packaging, documentation, and current availability with the supplier rather than relying on a generic listing.
This guide is intended for procurement teams, medicinal and process chemists, academic laboratories, and chemical distributors evaluating 2-bromophenylboronic acid. It focuses on product identity, common synthetic roles, specification review, and practical sourcing questions. It is not a substitute for a supplier’s current certificate of analysis (COA), safety data sheet (SDS), or project-specific process review. Buyers should use those documents to confirm details for the actual lot offered.
2-Bromophenylboronic acid is also described as 2-bromobenzeneboronic acid or ortho-bromophenylboronic acid. The “2-” designation means that the bromine substituent is adjacent to the boronic acid substituent on the aromatic ring. This arrangement gives the molecule two chemically distinct functional handles, although their reaction order and compatibility depend on the chosen conditions and substrate.
The boronic acid moiety is commonly used in carbon–carbon bond-forming chemistry, including Suzuki–Miyaura coupling with suitable organic halides or related coupling partners. The aryl bromide may be retained for a later transformation, such as another coupling step, when the reaction design and conditions allow. These are possible synthetic uses rather than guaranteed outcomes; reaction performance depends on catalyst, solvent, base, temperature, and substrate structure.
A common reason to consider this compound is the possibility of using its two functional groups at different stages of a synthesis. For example, a chemist may evaluate coupling through the boronic acid group while preserving the aryl bromide for subsequent chemistry. Because functional-group selectivity can vary, small-scale reaction screening is prudent before committing valuable material to a larger campaign.
The compound may be considered for the preparation of substituted biaryl structures and other aromatic intermediates. It can also serve as a starting material in route-development work where an ortho-substituted aromatic framework is required. Buyers should specify the intended application when requesting a grade or quantity, particularly if the material will be used in a regulated or tightly controlled process.
Listings for the same CAS number may differ in stated assay, appearance, packaging, and supporting documents. Do not assume that a catalog description represents the specification of every available lot. Request the current product specification and, where applicable, a lot-specific COA before confirming an order.
| Item to verify | What to confirm | Why it matters |
|---|---|---|
| Identity | Name, CAS number, formula, and structure | Helps confirm the requested positional isomer and prevent substitution errors. |
| Assay or purity | Specified value, analytical method, and lot result if available | Supports reaction planning and incoming-material acceptance. |
| Impurity information | Available limits or reported impurity profile | Relevant when impurities may affect downstream chemistry or process controls. |
| Documentation | COA, SDS, and any additional documents required by your organization | Enables technical review, safe handling, and procurement records. |
| Packaging and shipping | Pack size, container type, shipment conditions, and destination requirements | Confirms suitability for receipt, storage, and internal handling. |
The molecular weight provides a useful purchasing and reaction-planning reference: 1.00 g of pure 2-bromophenylboronic acid corresponds theoretically to approximately 4.98 mmol. Likewise, 1 mmol corresponds to approximately 200.83 mg of pure compound. These are calculated values based on the molecular weight and do not account for assay, water, residual solvent, or weighing uncertainty.
Start with the use case: exploratory research, route development, or a repeat manufacturing requirement. Specify the requested assay or purity threshold, quantity, and whether you need a particular analytical method or impurity control. If you do not have a fixed requirement, ask the supplier to state the available specification clearly so your technical team can assess it.
Check that the offered documents identify the same chemical name and CAS number as your purchase request. Compare the COA results with your internal acceptance criteria, and review the SDS for applicable handling, storage, and transport information. Where a particular test method is essential, confirm its availability before placing the order.
If you want to learn more, please visit our website Maison Chemical.
Ask for the offered pack size, packaging details, estimated dispatch or lead time, and any shipping restrictions relevant to your destination. These details can vary with inventory, order size, export documentation, and transport conditions, so they should be confirmed for the specific quotation. For repeat orders, discuss whether the same specification and documentation can be provided for future lots; do not assume lot-to-lot equivalence without review.
Pricing for a specialty intermediate can depend on quantity, grade, current availability, packaging, and destination. Minimum order quantities and lead times are likewise supplier- and order-specific; a public product name alone is not enough to establish them. Request a written quotation that identifies the product, quantity, specification, price basis, delivery terms, and document set.
For an initial evaluation, buyers may wish to compare the cost of a small research quantity with the requirements of a later scale-up. Confirm whether the quoted price includes packaging and shipping, and clarify the validity period of the offer. If your project has a target delivery window, state it in the inquiry so the supplier can confirm feasibility before order placement.
Use this checklist to compare quotations on more than unit price. A clear specification and a practical document review can reduce avoidable procurement delays, while a confirmed delivery plan helps align supply with laboratory or production scheduling. If an item is not available or cannot be documented as required, request clarification before substituting another grade or material.
One frequent mistake is treating all listings with a matching name as interchangeable without checking the CAS number and substitution position. Another is accepting a purity statement without asking how it is measured or whether the value applies to the offered lot. Buyers should also avoid assuming that storage conditions, shipping classification, packaging, or lead time are identical across suppliers; confirm these points from current documentation and quotation details.
A further risk is ordering on the basis of reaction assumptions alone. The presence of both a boronic acid and aryl bromide does not guarantee a particular sequence or selectivity under every set of conditions. Validate the material in the intended chemistry, and involve your technical team when scale, impurity sensitivity, or downstream requirements make performance especially important.
Maison Chemical supplies and exports specialty chemicals, including organic boronic acid products. For 2-bromophenylboronic acid, share the required quantity, target specification, destination, and documentation needs so we can respond against the actual purchasing requirement. We can discuss available packaging and quotation details, subject to confirmation at the time of inquiry.
To support an efficient review, include your preferred assay threshold, whether a lot-specific COA is required, and any delivery deadline. If you have a repeat-order plan, mention the expected frequency and quantity range so the sourcing discussion can account for continuity requirements. Final product, price, availability, and lead-time details should be confirmed in the quotation and accompanying documents.
2-Bromophenylboronic acid CAS 244205-40-1 is an ortho-substituted aromatic building block with a boronic acid group commonly used in coupling chemistry and an aryl bromide that may enable further functionalization. Its molecular weight is approximately 200.83 g/mol, making 1.00 g equivalent to about 4.98 mmol on a pure-compound basis. Whether it is the right choice depends on the intended route, required assay, impurity controls, and available documentation.
Before purchasing, verify identity, specification, COA and SDS availability, pack size, MOQ, price, and delivery timing for the offered lot. Send Maison Chemical your quantity and technical requirements to request current supply information and a quotation. This gives your team a practical basis for evaluating the material before placing an order.
If you want to learn more, please visit our website 2-Bromophenylboronic acid CAS 244205-40-1.